Thursday, September 26th, 2019

 

09:15 – 9:30    Welcome address

M. Paulsson, Associate Dean (Research) of the Medical Faculty

T. Šarić, K. Pfannkuche, Symposium organizers

 

Session 1:  Keynotes

Chairs: K. Pfannkuche and W. Röll

 

09:30 – 10:00  Jürgen Hescheler

Stem cells for basic research and regenerative medicine

 

10:00 – 10:45  Gabriele Pfitzer

Lessons from mice and men: How biomechanical properties of the sarcomere determine heart function in health and disease

 

10:45-11:15 Coffee Break and Networking

 

Session 2: Cell-Based Therapies

Chairs: F. Prósper and B. Fleischmann

 

11:15 – 11:45  Bernd Fleischmann

Plasticity in the neonatal and adult heart

 

11:45 – 12:15  Hossein Baharvand

Pluripotent stem cell-derived cardiac progenitors: A platform for synthetic developmental biology of the human heart

 

12:15 – 12:35  Early-stage researcher: Sarkawt Hamad

Differentiation of human iPSC-derived cardiomyocytes

 

12:35 – 12:55  Early-stage researcher: Stephanie Pieroth

Hydrogel spheroids as a new substrate for bioreactor culture

 

13:00 - 14:00 Lunch Break   

Company presentations

 

14:00 – 14:15  Product presentation

I&L Biosystems GmbH

 

14:15 – 14:30  Product presentation

Nippon Genetics Europe

 

14:30 – 14:45  Product presentation

 Miltenyi Biotech GmbH

 

Session 3:  Endogenous Heart Regeneration

Chairs: H. Baharvand and V. Khlebnikov

 

14:45 – 15:15  Felipe Prósper

Identification of mechanisms of cardiac repair using single cell transcriptomics of cardiac fibroblasts after myocardial infarction

 

15:15 – 15:45  Wilhelm Röll

Prevention of post-infarct arrhythmia by overexpression of connexin 43 within the murine myocardial scar

  

15:45 - 16:15 Coffee Break and Networking 

 

Session 4: Cell-free Heart Regeneration

Chairs: L. Kurian and A. M. Climent

 

16:15 – 16:45  Joost P. G. Sluijter

Advancing myocardial repair, do we need the cells?

 

16:45 – 17:15  Marie-José Goumans

Epicardial derived signaling and exosomes to stimulated endogenous cardiac repair

 

17:15– 17:30  Early-stage researcher presentation

Title pending

 

17:30– 19:00   Poster session and networking

 

Friday, September 27th, 2019

 

Session 5:  Organization, regulation and modelling

Chairs: J.  P. G. Sluijter and C. Dieterich

 

09:30 – 10:00  Andreu M. Climent

A global framework of the cardiovascular regenerative medicine: The TACTICs / CARE effort

 

10:00 – 10:30  Egbert Flory

Development and regulatory aspects of ATMPs

 

10:30 – 11:00  Peter Erlt

Chips-in-organs & organs-on –chips

 

11:00 - 11:30 Coffee Break and Networking

 

Session 6:  Non-coding RNAs in Heart Regeneration

Chairs: F. Engel and W. Zimmermann

 

11:30 – 12:00  Christoph Dieterich

Sequence, structure and interactions of circular RNAs in cardiovascular diseases

 

12:00 – 12:30  Leo Kurian

Making & breaking the heart

 

12:30 – 12:45  Early-stage researcher presentation

Title pending

 

12:45 - 14:00 Lunch Break

   

Session 7: Cardiac Tissue Engineering

Chairs: M.-J. Goumans and T. Šarić

 

14:00 – 14:30  Wolfgang Zimmermann

Tissue Engineered Heart Repair

 

14:30 – 15:00  Felix Engel

Heart regeneration: From cardiomyocyte proliferation to cardiac tissue engineering

 

15:00 – 15:30  Vitaliy Khlebnikov

Non-invasive monitoring of tissue engineering therapies with CEST-MRI

 

15:30 – 16:00  Marcel Halbach

Electrical integration of transplanted cardiomyocytes

 

16:00 – 16:15 Concluding remarks and closure